So, Space Cadet, I learned that it will take 6 weeks to get up to full speed on Lamictal today. I will take my first pill tonight and because I am on Depakoke, will take another pill Wednesday for two weeks then 50 mgs and so on. The only precaution my Doc told me about was BOLO for rashes, because these rashes are no ordinary rashes like chunks of skin could come off....doesn't sound like something I want to see. Hopes this provides a little insight.