Brian do you think neurotin has any effects on b-12 or any b vits..or has anyone buillt up a tolerance to high levels 3600 of the neurotin that is.

Sue, I think our bodies can & do build up a tolerance for pain meds, 3,600 mg is a heavy dose, but i am sure the initial dosage was much much lower and was tilted up slowly as the body become tolerant to the drug more was needed and on and on.
I know through my own personal experiences with Tramadol SR, there were a lot of times when i felt it wasn't working as good as is should, but i thought it was me becoming tolerant to that drug, so i done the reverse & cut the dosage down for a week or so [ wasn't a great week either ], then i would go back up to the normal dosage again and it worked every time, but thats me only.
I have no idea about Neurotin affecting Vitamin B, Rose or Mrs D may be able to help you on that one.
all the best
Brian