Thank you so much for the links! These are the clearest explanations I have seen. I was diagnosed last year with SF Neuronopathy (Ganglionopathy). It was confirmed by skin biopsy and the fact that my entire body is affected including my face and tongue. One thing that continues to baffle me is if the C fibers have indeed died back why do I not experience any deficit in my sense of touch? I only have these awful perceptions of burning and pins and needles. It would be awesome if you might point me to that type of information. It is a remarkable disease... Thank you in advance.