Originally Posted by biofed

Hi Folks, I'm 56. 4 months ago, my wife, also 56, noticed a fasciculation in her thumb which has progressed to more generalized twitches with some calf cramping and leg pains, mostly after exercise. No weakness. About 6 weeks after her symptoms started, I began to have fasciculations, mostly right calf, at first, then also more generalized I also have cramping, mostly in feet and R calf, and my feet also hurt upon standing and walking; "rocks in shoes". My hamstrings also hurt a lot after exercise; a "Charlie horse" that seems too soon for that to typically occur. My wife has also had that symptom. Neither of us have any objective weakness, and neurology exams and EMG/NCVs on both of us were negative. My Lyme ELISA was equivocal; further Lyme titers pending. (We had travelled in South America, including a rain forest, one year ago).

Any thoughts on the above, and the possibility of a viral explanation for our symptoms occurring within weeks of each other? I've read about possible viral causes of neuropathies and of Benign Fasciculation Cramp Syndrome. Thanks.