The straps size, type of material, weight of the bag, all these things can make a BIG difference, and it's just something she'd have to try on. Instead of notebooks, loose leaf papers in a peachy folder would be lighter.

If vibrations and noise bother her, it's going to be really tough. Maybe even a part time schedule should be considered? That way she could meet friends and socialize, but could do some work from home?

Even scheduling her in classes that have fewer students might help. The counselors will know which are good, just not quite so popular.

My son was given special accommodations to take online classes at various times because he had gone through an accelerated math program through John Hopkins and Stanford. BYU had some interesting choices for online classes, etc. An opportunity to be able to come home early or go to a quiet library 1/2 way through her day might be really appealing.

My adaptive PE class was great btw. There were 6 of us, instead of 60. And it was similar to PT in many ways. They might allow her to substitute a water exercise program (warm water classses at the YMCA are often available) as well.

Good luck to you both!