Our relative w/ Bipolar Illness, age 24, was complaining of shoulder pain for two weeks and eventually went to the ER.She was given Tramadal. We were on vacation at the time.

Right after she took her first dosage of Tramadal...something REALLY BAD and totally out of the ordinary happened.

She got into signficant trouble. Nothing to this extent has ever happened before. It is huge and likely life altering. We are deeply saddened. I didn't see her, so I can't report on how she was acting, etc.

But I do know that she did this "thing," that got her in major trouble right after taking this medication. She has never taken a pain reliever, of any kind, (other than over the counter things like Motrin) before.

Has anyone had a manic (or simply bad) reaction from Tramadol before?

Thank you.