I stopped taking prilosec after 10 years of use. I had many alarming symptoms of PN and PPI's seem to be the cause of it for me. To help combat the GERD I lost weight, ate healthier and took supplements listed on this site. I rarely feel the effect of heartburn anymore although I need to avoid high acid foods.

MrsD had some great insight about how Omega 3 fish oil helps control GERD. I suspect it has something to do with the anti-inflammatory abilities (EPA) of the supplement. She can offer more insight on this than me.

Other nutrients that PPI's can reduce besides B12 are folate, magnesium, iron and calcium. Additional B12 , folate and magnesium all helped me feel better over time.