Mu Gerds was not cause by PPI's. I did and had taken the priolsec. My PN turned out to be RSD, and not caused by my new PPI. Before medication or change to vitamine suppliments it is always best to consult with a doctor. Even though I took PPIs' it was not good enough to stop the progression to Barretts esophagus. My doctors didn't believe me when I said my stomach still hurt with Nexium and Priolsec. It took a scope to figure out what was wrong with me and I did follow all my doctors directons. ginnie