I've been meaning to get back on this thread and share the experiences that I've had with respect to starting on LDN 1 day short of 2 weeks ago, but I thought that it would be best to give it at least a 2 week trial first though.

I'm happy to report that the experience thus far has been a very positive one. It did take a little experimentation to find my "sweet spot" with respect to timing of the LDN dose; and in the end it turns out that for me, around midnight is the best.

By then I've had around 2 hours of actual sleep and then around 1:00 I lay back down and at least try to get another 3 or 4 hours in. This usually occurs in 30-60 minute stints, but I do get it now where before LDN, it wasn't always the case...even with Baclofen to control the spasms.

There are still nights when I hardly sleep at all, but thinking back, these were also the nights that I took the LDN earlier or later than midnight. So even if it is in a slight way, I think that the LDN has improved the quality and the quantity of sleep that I get.

Here are some of the things that I've noticed:

- fewer and less severe periods of cog-fog (this is a HUGE thing for me, and I'd stay on it just for that reason)

- less fatigue during the day, but when it does hit, OH Boy...It's like it has been saved up or something. Good that this occurs at the end of the day when it does occur, as I just take advantage of it and get some extra sleep in. Doing that does seem to mess up my already messed up sleep cycle-times though. I figure that it will sort itself out so like always, I just take one day and night at a time

- less need for recovery after physical activity and I can go for longer periods without having to rest

- less neurological stuff in general; shooting pain, buzzing, etc. although I have had a few days in the past 2 weeks when my feet and lower legs went numb. I have no idea if I was heading into a TM flare, or if it was just a carry over from past ones or what. I also don't know if LDN interfered with the progress of it in anyway. Generally, when I get that symptom it does last for longer than it did though.

- less hair falling out of my already scantily tressed pumpkin (LOL)

- more balance in general but I'm still unsteady when the fatigue hits and maybe a little more so

- more sensitivity of the teeth; I have no idea why that would be, as my oral hygiene, diet etc has not changed. It's another wait and see thing.

- more and longer periods of clearer vision; but also more extremes in vision; either really good or really bad

- more muscle twitching; its not painful, just annoying

- more perspiration (Ok for your decorum sensibilities, Sally? -LOL), and more need for deodorant (Sorry...there's no nicer way to say it than I can think of right now.)

That's about it, but I'm looking forward to seeing how increasing the dose goes when the time comes. I know that I'm not ready to do that yet though.
I did try on three occasions to go with 4.5mg (because I was either too uncoordinated to prepare the 3 of the 3 mg dose from 2 of the 4.5mg capsules, had forgotten to do it before hand, or was just too tired/lazy. The wonderful thing is that there were those different reasons. Before starting LDN, it would have been all of them together.

Anyway, it seemed to make me a little too 'speedy' in the morning, as well as less tolerant of situations as well as others by the afternoon (ie; cranky, moody). Very few medications are worth that side effect in my world.

Will keep you posted.

With love, Erika