Thank you everyone. I spoke with my Dr and he said that the side effects I am having are not desired effects and to try a couple more shots and if the side effects dont improve that we might have to try somthing else. I pre and post medicate and drink plenty of water. I just feel like crap and I almost feel like my MS is worse now that I started treatment. I start feeling the side effects within 1-2 hrs and it goes like this...start getting a little cold one hour mark,by the 2nd hour the fever starts, then feels like I have to constantly stretch my muscles, then my muscles feel very tight and start jurking around which I cant controll all within 4hrs, then extreme cold blood presure drops heart rate goes up I know its because of the fever all this lasts about 12 hrs or so. Then I feel like crap for days. I do shot #4 this Friday nervous about it because I am a surgical tech and I will be on call this weekend and I know that there is no way I can drive let-alone work the first 24hrs after the shot, so we will see. Thank you all for your positive words of encouragement. I hate that anyone has to go through this but it does help to know you are not alone.