For me these are early days in my MG diagnosis and treatment, having just completed 4 days of IVIg last week and being on Predisone for 8 days so far and Mestinon 14 days so far (now at 45 mg's four times during day). But I think that I am seeing improvements with Mestinon. Better swallowing with less or no choking, more successful deep-breath attempts, more general energy, able to speak for longer periods without a shut-down (although I constantly have a weak, horse, voice that sounds like Marlin Brando in The Godfather). But again, with all these treatments and drugs in recent days its hard to tell what is doing it. I am getting some of the published side effects of the Mestinon, however, such as smaller eye pupil size (which is blurring my vision somewhat), frequent urination, a bit of a "wired' feeling...but all manageable. Best to all...Mark.