I have taken Longvida RD (a brand) as part of my constantly refined regimen for quite some time. I didn't expect symptom relief but at a capsule twice daily I haven't had side effects either. What I am hoping for is a positive effect on progression because of its neurogenesis and anti-inflammatory properties plus its ability to pass the BBB. Here is more info about Longvida: http://www.longvida.com/Curcumin-Selected-Data.html

I take other substances with potentially beneficial properties, too, like andrographis and Baikal skullcap so it will be hard to judge the contribution of Longvida, but I take it anyway just in case.