The main ingredient is pharmaceutical cocaine. That's right - no misspelling. This stuff lasts about as long as coke does too. It says to put it on 3-4 times a day - that should be your first clue. Sticky as hell, the consistency of airplane glue. I guess you're supposed to take your compression socks off a couple of times at work, put the sticky stuff on, and try to put them back on within a half hour. I reckon I shouldn't complain. It helped me for about an hour. Although I was really disappointed it didn't make my feet horny.