Hi offinthedistance,

Unfortunately, progression and/or an increase in symptoms can happen even when MRIs are stable or improved.

Many find the MRI does not match up with how they feel, such as; a person's symptoms are worse or they are having a relapse but the MRI shows no changes or the person feels fine but the MRI shows active lesions. Sometimes the MRI will match up to how a person may feel.

Bottom line: There is more to this disease than what an MRI show. It is always better to treat the patient, not the MRI.