Hi Jilly,

I have been taking Tramacet as well as Zoloft. I asked my pharmacy several times if Tramacet could cause severe bruising and was told no. I went to my doctor and showed him my bruises and he immediately sent me for blood work. He checked both meds and said that this side affect was not listed and was going to contact his supplier. I have taken Zoloft before and never had a problem with it so I thought it might be the Tramacet (newer drug on the market and I haven't use it before). I looked up Zoloft on the internet and found that it shouldn't be taken with Tramadol (which is one of the drugs in Tramacet) because bruising for no apparent reason can occur. We are talking purple grapefruit size bruises all over my legs and arms. I would have pains in my legs and then the next thing I new I had yet another bruise.I am now waiting to find out if I have liver damage. Dana

Has anyone else had this same problem?