I was on betaseron for 9 months, 10yrs ago. Had horrible reactions to it so I dropped it. Got scared off of dmd's til this past Oct and Dec when I had 2 really bad flares. 4 rounds of steroids later, and neuro said its time for a dmd. So he said the only ones I could try since beta caused me so many problems, was ty, gilenya and copaxone. I went for the least risky, copaxone. This is the last one I'll try for now until further studies or whatever are done on the BG12 and that new one I think is call Auggubie, or something like that. From my understanding the BG12 is just as risky as gilenya, so Im pretty much crossing that off my list of hopefuls. Ive wanted to try LDN, but I have a "contract" with copaxone that I have to be on it for one full year unless I develope an allergy to it. Im 7 months in, so not much longer. Doc is really pushing ty and omg, you should see all those MS patients in the infusion room. ALL but me were there for TY! Im sorry, but the chance of a deadly brain infection is enough for me to say NEVER. I have the worst luck with things. If the package says may cause drowsiness, guaranteed I will be out cold. One neuro put me on .5 valium for my spasms, knocked me cold for no less than 8 hours. Did nothing for the spasms! One med said may cause stomach cramps, well, guess who got 'em. Another said may cause migraines, well, same old story. I actually landed in the hospital because of a med side effect. Ive learned the hard way to take side effects seriously. If I have "graduated" to SP, then maybe I can stop all the shots and just do symptom management.