My neurologist suspected a hereditary neuropathy from the first visit. EMG/NCS was abnormal. She sent me to johns Hopkins where I had the skin biopsy which confirmed advanced SFN, another NCS confirmed large fiber neuropathy as well, with muscle wastage. I did not want a spinal tap or all the Athena tests, although they offered to do them, as there is no treatment. Both neuros agreed with my decision and threw me back to my PCP for pain management. My feet and ankles have noticeable muscle loss in the past two years. They are really thin.

But this is expected with my DX. Mrs. D. Is right, a sudden change is unusual and could be a lot of things, worth investigating. Have they checked your circulation?