Last night I stayed up late working on friend's mri & forgot to take the asprin before bed.
Awoke like clockwork around 5am to right leg giving a quick JOLT every 30 seconds. Luckily I had baclofen stashed for times like that & 1/2 hr later, went back to sleep.
Moral of the story, asprin absolutely works. Another night i'll try tylenol to see if it's the pain med effect or circulation though I don't know how tylenol or advil do their thing? Mech of action in tech words anyone?