I had been on baclofen & it didn't affect the spasticity at all. When I switched to my present neuro he switched me to zanaflex & I was on the maximum dose...til I ended up in the ER a couple of times with low pulse/BP. I was taken off completely. My spasticity is increasing after 6 weeks of remission...but I don't want to end up ack in the ER. I miss not having spasms...