Methadone comes in small (5mg) and up tablets. It is very strong, and very effective. If you take too large a dose, like anything, you WILL get sick. I started very low and slow under a Drs supervision.
I had very little constipation compared to fentynal or morphine or vicodin.
I had very little side effects at all. I didn't notice a buzz either like you get from vicodin or oxycontin. It didn't make me sleepy either, but I don't take large doses. I don't have to. 5mg every 6 hrs works great for pain reliel for me. I get a 3 mo. script every 3 mos. Nacho