immunofixation and immunoglobulins are looking for long chain antibodies that the body makes which can then clog the blood, reducing blood flow to the fingers/hands, toes/feet, which can reduce circulation there.
MGUS is one condition that can be identified. Severe elevations of certain ones indicate multiple myeloma, but modest elevations are more likely to cause peripheral neuropathies. Some of our PN posters have MGUS.
http://en.wikipedia.org/wiki/Monoclo...d_significance
The fixation test is a chromatography showing bands of proteins that are put past an electrical field to separate them out.
The most common band shows MGUS (elevated IgM.)
These tests are more specific than sed rate or C-reactive protein, because they identify specific antibodies in the blood.
The sed rate and C-reactive show general inflammation, but not where it is coming from.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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