hi
not enough info for me to offer much imho. sounds like this dr. going back to square one, seeing for himself what's going on? does he know the other neuro?

50/200 CR, "CONTROLLED RELEASE" works better in some people in providing more even relief than the "ER" version and less dyskinesias but if the regular sinemet isn't doing the job it isn't going to work any better imho. which is why from what you said it sounds like this new neuro is wanting to verify for himself how the different tools in his bag works.

can't imagine sinemet CR would give any better relief when at it's best than sinemet ER plus comtan but i'm no expert.


keep in mind the bioavailability of CR is 30-40% less than the ER version so the doseage usually will be higher than the ER dose.

can't comment on DBS;s but read you have to respond to sinemet to qualify.