This is getter interestinger and interestinger...

Rick posted a year ago about his improvement in symptoms by switching his high blood pressure medication to perindopril, which is one of two in that class that cross the BBB. His PD symptoms improved, as he reported here:

http://neurotalk.psychcentral.com/sh...ssure+medicine

Thanks, Rick!

This makes total sense, assuming again that vascular compression is an issue in PD: if you have vascular compression in the brain, and take a hbp drug that does not cross the BBB, any compression inside the brain will NOT be alleviated because the drug cannot reach it, the BBB keeps it out.

Conversely, if you just happen to take a hbp drug that does cross the BBB, then any compression you have inside the brain WILL be affected, and you would notice an improvement in your PD symptoms, I would think.

Rick, if you see this, are you still taking the peridopril and if so, how are you doing? If not, what caused you to quit taking it?