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Member
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Join Date: Apr 2010
Location: GulfCoastSouth .... April 2014 rudely displanted to the cold wet windy gloomy NW coast.
Posts: 675
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Member
Join Date: Apr 2010
Location: GulfCoastSouth .... April 2014 rudely displanted to the cold wet windy gloomy NW coast.
Posts: 675
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Unfortunately, what Mark refers to, can be true for many. Can be disconcerting.
Quote:
Originally Posted by Mark in Idaho
Recent research shows that there are many physiological conditions that overlap between Alzheimer's and mTBI. The beta-amyloid plaques of AD are also seen in mTBI.
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http://www.uphs.upenn.edu/news/News_.../brain-injury/
"In this study, researchers examined post-mortem brains from 39 long-term survivors of a single TBI, extending the survival time from 1-47 years survival after TBI, and compared them to uninjured, age-matched controls."
"TBI survivors showed a high density and wide distribution of neurofibrillary tau tangles and amyloid-beta plaque pathology far beyond what was found in controls. Specifically, about a third of the cases showed tangle pathology years after a single TBI, similar in appearance to the tangles found after repetitive TBI and in neurodegenerative diseases such as Alzheimer’s disease. Moreover, the amyloid-beta plaques were not only found years after TBI, but the majority of cases displayed diffuse as well as "neuritic" plaques with the same character as "senile" plaques also found in Alzheimer's disease. This suggests that years after a single TBI, amyloid-beta plaques may return and become neuritic."
"The present findings, showing that two hallmark pathologies of Alzheimer's disease can be found years after a single TBI, may provide a pathological link with the epidemiological observation of an increased risk of developing Alzheimer's disease. Moreover, future research to better understand this long-term neurodegenerative process after a single TBI may reveal important targets for treatment with emerging anti-tau and anti-amyloid therapies."
"The study was funded by the U.S. National Institutes of Health."
You can read the whole article published by Univ. Penn. Health Sciences and USNIH"
http://www.uphs.upenn.edu/news/News_.../brain-injury/
Theta 
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50s Babyboomer; 2008 high-impact rear-ended/totalled-MVC, closed-head injury->pcs ... "Still dealing with it."
1993, Fell on black ice; first closed-head injury; life-altering. // 2014 Now dealing with Peripheral Neuropathy, tremors, shakiness, vestibular disorder, akithesia, anhedonia, yada yada, likely thanks to rx meds // 2014: uprooted to the cold wet gray NW coast, trying to find a way back home ... where it's blue sky and warm!
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Each and every day I am better and better. I affirm and give thanks that it is so. // 2014-This was still true for me last year, I truly felt this a year ago. Unfortunately it holds no meaning for me now. Odd, it was the Theta mantra for years. Change change change.
Last edited by Theta Z; 10-12-2012 at 09:35 AM.
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