About "brain issues" in MG:
http://www.ncbi.nlm.nih.gov/pubmed/11166079
Note that the first line says, "Most individuals with myasthenia gravis (MG) complain of cognitive impairment........."
I definitely notice a difference in my ability to think and remember.............even when I'm NOT on Topamax for migraines.

When ALSO on Topamax, I'm dumber than dirt.
Just in case you are wondering, I'm currently a certified idiot.