I recently received the results back from an MRI of my brain and a paraneoplastic panel that was sent to the Mayo clinic.
The MRI showed 3 - 4 tiny foci and the paraneoplastic panel shows a positive hit on Neuronal Acetylcholine Ganglionic Receptor Antibody (Alpha 3). .09 nmol/L

Some of this seems to point to dysautonomia or POTS or Guillain-Barre

Does anyone have any ideas of what this could be? Is there a connection between the MRI and the antibody?

I had someone who reads MRI results for the brain everyday say it is not uncommon for a person in their 40's to have some spots in white matter. You will have more as you age.
But, the antibody that I tested positive for is quite troubling.

Here are some of the symptoms I am experiencing
PN symptoms in hands and feet
Twitching all over my body
Fullness, ringing in ears - Tinnitus
Feet become cold and fullness is gone. Then after some time the bottom of feet will become bright red and toes may become purple.
Constipation (Bright red blood in stool)
Sometimes get dizzy when I stand up
Sometimes I become tired/lethargic suddenly w/out activity
Brain fog
Drymouth (Could it be the nortriptyline)
Flush face- red nose - ears red - (all are hot to touch) happens alot when I get upset
Sometimes have twitching around eyes - have has some around my face and all over my body but mostly in legs near calves
Urination flow start/stop, usually at night (Had this issue with Cymbalta - may be the nortriptyline)
Seems the only part of me that sweats now is the bottom of my feet
Hands become very cold and fingertips wrinkle - Fingernails have a light purple tint - Then hours later after being cold the hands will become bright red and very hot.

Thanks in advance...