I'm 18 months since diagnosis, 3.5 years since symptoms, 15 months since starting prednisone. Can't do without it. Mestinon (30 4x/day) isn't enough, so I have prednisone (30 mg/day) and Imuran (150/day) too. I'm considered mild-moderate seronegative generalized MG. I had a robotic thymectomy last December, and have worsened since then, mostly in the last couple of months.

Prednisone has given me the moon face, curved upper back, fatty chin, munchies. I am on weight watchers to help maintain the weight that comes along with the munchies. I do not have stomach issues with these meds. I haven't had tests in awhile to see what it's doing to me internally, but like I said, the pros outweigh the cons for me. I'd be working part time instead of full time and unable to spend quality time with my kid if not for the prednisone. I was on 25 mg/day for a long time, tried to wean down to 15 earlier this year, and now am up to 30/day as of a couple of weeks ago.

Best wishes to you!
Susan