Hello, I'm new to this site and was recently diagnosed with Myasthenia Gravis. Years back a test came back positive in the modulating part of the acetylcholine test, but then showed up negative on other tests. I have had muscle weakness to the point of being hospitalized for breathing problems. Recently I had an anti ach receptor antibody test and it showed me positive again modulating at 41%. I'm not even sure if this is the same type of test I've taken at other times. Anyhow, my Rheumatologist tested me for various other autoimmune diseases and even Lyme disease, and this was the only thing that was positive, besides high c reactive protein. He diagnosed me with Myasthenia Gravis and I'm not sure if this test alone is enough to give me a diagnosis. The doctor put me on Mestinon and it helps me with my breathing problems and the weak muscles in my back however, my neck and swallowing muscles are weaker from taking this med. This morning, I couldn't remember if I took my pill or not. I felt like an elephant was sitting on my chest and I could only get up to do chores in ten minute spurts before resting. All my muscles felt heavy. I think I probably didn't take it this morning. I waited until the afternoon to take my next pill and felt better afterwards. Is this a normal reaction when any of you miss a dose? I take 60 mg every eight hours.