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Old 11-10-2012, 03:54 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

I predict your doctor won't know at all about the two versions.

If you take D3, you won't need the other at all.

The only reason the doctors order it, is because it remains in their old outdated therapeutic references.

You can go ahead and take it. But don't expect much from it.

Quote:
Am J Clin Nutr. 2006 Oct;84(4):694-7.
The case against ergocalciferol (vitamin D2) as a vitamin supplement.
Houghton LA, Vieth R.
Source

School of Nutrition and Dietetics, Acadia University, Wolfville, Canada. lisa.houghton@acadiau.ca
Abstract

Supplemental vitamin D is available in 2 distinct forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Pharmacopoeias have officially regarded these 2 forms as equivalent and interchangeable, yet this presumption of equivalence is based on studies of rickets prevention in infants conducted 70 y ago. The emergence of 25-hydroxyvitamin D as a measure of vitamin D status provides an objective, quantitative measure of the biological response to vitamin D administration. As a result, vitamin D3 has proven to be the more potent form of vitamin D in all primate species, including humans. Despite an emerging body of evidence suggesting several plausible explanations for the greater bioefficacy of vitamin D3, the form of vitamin D used in major preparations of prescriptions in North America is vitamin D2. The case that vitamin D2 should no longer be considered equivalent to vitamin D3 is based on differences in their efficacy at raising serum 25-hydroxyvitamin D, diminished binding of vitamin D2 metabolites to vitamin D binding protein in plasma, and a nonphysiologic metabolism and shorter shelf life of vitamin D2. Vitamin D2, or ergocalciferol, should not be regarded as a nutrient suitable for supplementation or fortification.

PMID:
17023693
[PubMed - indexed for MEDLINE]
and
Quote:
Rev Med Interne. 2008 Oct;29(10):815-20. Epub 2008 Apr 11.
[Vitamin D2 or vitamin D3?].
[Article in French]
Mistretta VI, Delanaye P, Chapelle JP, Souberbielle JC, Cavalier E.
Source

Service de chimie médicale, CHU de Liège, université de Liège, domaine du Sart-Tilman, Liège, Belgique.
Abstract
PURPOSE:

Nearly one billion people around the world are deficient in vitamin D and need to be supplemented. Vitamin D is available in medicines and fortified foods. It is available in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
KEY POINTS:

The pharmacopeiae consider these steroid hormones as equivalent and interchangeable. However, several studies have showed that serum level of 25(OH)D is increased more effectively with vitamin D3 than vitamin D2. Vitamin D2 has shorter plasma half-life and a lower affinity for the vitamin D binding protein, the hepatic vitamin D hydroxylase and the vitamin D receptor.
CONCLUSION:

Vitamin D2 should not be regarded anymore as suitable for supplementation or fortification. Currently though, it is still the most used in some countries such as Portugal and Australia.

PMID:
18406498
[PubMed - indexed for MEDLINE]
Have you read this link and watched the two videos on it?
http://neurotalk.psychcentral.com/thread92116.html

Now is the time before your next appointment.

Things are changing rapidly about Vit D supplementation.
It will be a while yet for doctors to understand it all.
It is not unlike the poor interpretation of B12 levels, which continue now a decade later inspite of medical continuing education to the contrary about making 400pg/ml the new low for humans.
This article on THAT from 2003, written for doctors:
http://www.aafp.org/afp/2003/0301/p979.html
There are still doctors who don't understand ORAL B12 treatments today.

And BTW both forms are fat soluble. I can't see any reason for using D2 (ergocalciferol) today at all. D3 is even less expensive.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

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Weezie looking at petunias 8.25.2017


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