Well, again, I am not doubting Sinemet can work for some people. In my mother I have yet to see any demonstrable benefit, and the neurologist says as much. The neuro suggests we just keep changing the dose until we see if my mother responds. Why we need medicine in the first place is not clear since my mother never complained of any symptoms of PD. It says as mcuh in the doctors notes from her first diagnosis. But I know the inclination of allopathic doctors is to give meds at the drop of a hat.

It's always a cost/benefit analysis, and in this case I see many costs, but not sure of any benefit. All my mother's close friends are wondering why the past few months she has had all kinds of problems. We could chalk it up to age and forget about it and double down on Sinemet. But it would appear to me that whatever the results of now reducing dosage (improved sleep, glimpses of better mental function, making jokes, etc.) the previous increase in dosage definitely had a part in negative side effects. It is a drug (like all of them) that in some circumstances, can be dangerous. Otherwise there would be no warning label on it. For example one circumstance it can be dangerous is in amounts beyond what your specific body can tolerate. Evidently this threshold was crossed in my mother's case. The neuro said this was likely so, herself, given my mother's symptoms.