cymbalta has been discussed here on this site a number of times so for more info look in the archives, but i was given it in addition to my usual neurontin and by the third day was on a cloud somewhere ... oh i was comfortable alright but could not even get out of bed. i really should have been taken to the hospital, i was that bad but my husband did not realize it. it wore off. there have been writing on it more recently stating that you should not take it with neurontin, and i would think also not with topamaz or lyrica since they are similar, but ask a pharmacist to check for info on combining your meds.
i think there was one person who said it worked for them.
i was actually tempted to take it again because i felt so comfortable ... so i put it down the toilet. it was the most pain free days i ever had.
best to you, joan