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Old 11-17-2012, 12:57 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Valproate has some down sides.

1) It can cause hormone disruptions in men and women.

2) it is hard on the liver

3) it causes a depletion of carnitine over time. This itself can lead to fatal events.

So valproate is not very popular anymore, when at one time it was.

Most people with nerve pain use either Neurontin or Lyrica for their anticonvulsant. Tegretol and Trileptal can cause hyponatremia (low sodium levels).
Some use Topomax but that has side effects on the kidney (stones) and eyes.(glaucoma)

Doctors generally feel that Neurontin and Lyrica have the lowest serious side effect profile.
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"Thanks for this!" says:
KristaQ (11-17-2012)