http://www.ispub.com/journal/the-int....LjKlYbwN.dpbs
I have needed oxygen on flights. I remember one in particular. I would have not have come off the flight had I not received it. Lucky me, I get to rely on the airlines for it. If I ever must fly (I don't unless threatened) and I don't get it, I'll have the rare opportunity to go from immediately from flying to six feet under. (And yes, I have almost blacked out on other flights, gotten off with extreme weakness on others).
I sort of doubt most people on here will be that bad off but I wouldn't guarantee my own survival on a flight with no medical support and even with it, it's a gamble.