Thanks Annie,
I really liked this sentence:
Quote:
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jet aircraft are designed to operate efficiently at high altitudes but the human body is not. Humans are land animals, evolved to exist comfortably close to sea level at a maximum speed (and that for only very short sprints) of little more than 15 miles per hour. Anything else is a foreign, and potentially lethal, environment. Any time we operate above the altitude of acclimatization (the altitude where we normally live), risks exist. No matter how you perceive your performance (and despite all the bravado and tough war stories) the body will still respond to the atmosphere in which it is operating and be affected by gas concentrations and ambient pressures.
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MG patients lose their ability to adjust to changes in the environment.
This is a very reasonable explanation one of my respiratory physicians gave me for the fluctuations of MG. He said that even relatively minor changes in barometric pressure, temperature etc. which occur in the atmosphere can lead to decompensation in someone with decreased reserves.
Let alone, the much more extreme changes that occur during a flight.