I'm glad you started this thread. My neuro hasn't really addressed depression as a component of MS, but my PCP is on top of it. I think you're right that it probably doesn't matter whether it's an MS symptom or not--would treatment be any different? As you said, it's tricky.

On some level, even though I KNOW it isn't true, there is the feeling that if it's not a symptom of MS, that I should somehow be able to control it--you know: cheer up, don't wallow in self-pity, look on the bright side, "have more faith", etc.

Was I depressed as a teenager? Or was that typical teenage "they'd be sorry they treated me that way if I died" angst? Did I have clinical depression in my twenties? Or was that situational due to a troubled marriage, physical problems, etc.? Or was that a symptom of the MS I didn't know yet I had? No way to know, ever.

I hope this thread/conversation continues, as I know I'll have plenty more to say during those sporadic times that my brain cooperates!