I'm thinking that depression is just a part of MS as you keep losing something you once could do. I know that depression is part of the grieving process at least as far as CMT. We are constantly in one stage of grief or the other. Something we could do is always being taken away. We know what causes CMT and that doesn't make any difference. There is no cure/treatment for it at the present time. I just try and deal with it and roll with the punches.