I had a knee replacement and I have small fiber neuropathy. I have Raynaud's in my hands and feet as well. The knee replacement didn't change the outcome or progression of the SFN, as my symptoms are equal in both feet/ankles/lower extremities and I do not need a knee replacement on the other side (I had post-traumatic arthritis and had no cartilage at all left in my right knee.).

As far as waiting, if you are in as much pain as I was, and in both knees, I can't imagine waiting to have it done. I have never regretted the surgery for an instant as at least my KNEE doesn't hurt anymore, and it was awful. Luckily, I am allergic to fluoroquinolones (and nearly all other antibiotics - not so lucky there), so they always give me a dose of IV Vancomycin in the hospital when I have surgery.

Best of luck to you,
Deb G.
KY