Thank you for your helpful input. She has not been testing for porphyria or erythema nodosum so we will talk to her doctors about getting her tested. She has had a punch biopsy of an active area in her hand and it sparked a whole spreading of intense pain,swelling and discoloration very quickly up her arm to her shoulder. The biopsy did not reveal any evidence of anything including not a single red blood cell.

Thanks again for your help. We are desparate for any information that will provide insight.

Jackie