Yes, there is a study showing up to 30% less absorption from
lipoic acid when food is present.
I really think using the new highly soluble r-lipoic acid stabilized, is easiest. 100mg a day, and that is it! One does not need high doses then. I'd still take it on an empty stomach though. But it is your choice after all.
I use Doctor's Best brand.
The old alpha lipoic is 50% inactive isomer...the S-form. Our bodies don't make this form, as it is a result of chemical synthesis by manufacturers. So out of that 300mg dose only 150mg is the active R form.
I don't think it matters about dividing the doses. If you take it all at once, it will only block the transporter for it for a short while. Biotin and B5 share this transporter, so keeping a window open for them may be best all around for you.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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