I admit that I have tried skipping meds to see if they really do help. I take Adderall XR and have tried to skip it and my fatigue level goes through the roof. Ampyra didn't do a thing for me and increased my fatigue level.

This is not a med that your life depends on like blood pressure or antidepressant. So stopping it for a bit is not going to affect anything crucial. I think you have gotten your answer though and see that it helps you after all.