Erratic blood pressure, insomnia...multiple days in hospital with misdiagnosis over yrs. Based on amount of lesions in brain & spinal chord they suspect I may have had it since my teens (now in md-40's). Last 6 years there were ER trips and hospitalizations for stroke level BP and "exhaustion" they only found the MS about 18 months ago. Seems all those hospital incidents were more than likely relapses. I always thought it was funny how I could be exhausted and hyper on 2-3 hrs sleep at the same time. I wish the best for your ex-wife and tell her to trust what she feels with her body and not to let the doctors quit until they figure it out.