Quote:
Originally Posted by southblues
I don't know if this is true because I just thought it up myself, but I am thinking that heat allows acetylcholinesterase to work properly. Going on that assumption, I would think that cold would inhibit it. Then based on this idea, cold would work the same way that mestinon works; decreasing acetycholinesterase therefore increasing acetylcholine.
Anybody know if that is right?
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I think you may be right. I read in an article on the internet (I do not remember what site so I do not know if it is reputable) that the bigger muscles are more affected by MG because the bigger the muscle, the hotter the muscle would "burn" so they are affected sooner. I know that is true for me. My muscles most affected are the thigh, hip flexors, latts, deltoids and pectorals.
thanks
kathie