I don't know if this helps or not, but some companies have a special program for Medicare patients. I'm on Medicare because I have SSDI, and when I was taking Tysabri I got a special Medicare price--I think we only paid something like $10 a month for the Tysabri, and then another $30 to the hospital for infusion charges.

It helps to talk to a rep from the drug manufacturer and find out as much as you can about discount payment programs. Biogen, for example, which produces both Tysabri and Avonex, has a number of programs for people both with and without Medicare.