Thread: Folic Acid
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Old 01-14-2013, 03:45 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Folic acid is not the active form for folate you know?

Most people with low B12 will have high folate in tests, because of the methyl trap...
http://en.wikipedia.org/wiki/Folic_acid

Because many foods in US are now fortified with folic acid,
deficiency is less common. However in those with MTHFR enzyme defects, methylation (activation) does not happen, so folic acid is useless.

There is some thought that folic acid prevents or competes with
folate at the blood brain barrier. That means real actions of folate may be blocked in some people. Natural folates occur in veggies, etc.

Folic acid deficiency shows up as anemia pretty quickly, and can be identified that way.

Methylfolate is included in Metanx vitamins. But we don't see many people here who post testing results showing low folate. So how involved in PN it is remains confusing.
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