I'm currently having my first, KNOWN, MS flare up. I start 3 days of IV solu-medrol tomorrow. I've gotten 3, 5 day courses of it before for the optic neuritis that I went through about a year and a half ago and it worked well to bring back my sight fully after the 3rd course. This, however, is the first time I am getting the solu-medrol for the MS, and my question is.. Will I notice a difference rather quickly or will it take a while before the medicine takes effect? I'm in severe pain and now am unable to use my right.. barely. I have two young boys who require my attention and care and am hoping that the medicine takes effect quickly. Anyhow, any information would be much appreciated!