Hi All! It's been awhile since I have been on here due to the fact that ive been going through alot. I was on imuran for about 15 years. On 150 mg daily. My M.G. specialist raised the dose to 200 mg daily. Well lets just say that it took less than a year for it to really affect my liver. I began feeling terrible all M.G symptoms were bad. I turned yellow even and after many er visits, blood tests and finally a great liver doctor that did a liver biopsy figured out the dosage of imuran was to high for me and had my liver at toxic stages. In May I was completely taken off Imuran and felt better. I was managing on 28.5 mg of prednisone and ivig treatments every 3 weeks. I have tried cellcept since because my M.G specialist said I need something other than ivig to get me to be able to lower the prednisone. Well cellcept made me feel horrible! I was weaker than had been so we stopped it after only a week. I have also been seeing my Endocreinologist because a couple of years ago I was diagnosed with hiashimotos thyroiditis. My blood levels have been normal but alot of symptoms have been pointing to my thyroid acting up. I went twice to the endocrinologist and finally he put me on a small dose of levothyroxine. I feel better in some ways but just the heaviness i feel is terrible. My arms and legs are so heavy. The specialist as well as my local neuro want to try imuran again but start extremely slow and not go any higher than I was before. So at this point I dont know if it's M.G or thyroid issues or both. I know blood tests aren't always accurate especially with thyroid. Any suggestions?? I feel hopeless!