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Old 05-05-2007, 06:39 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb not the Gabapentin...

This drug is not metabolized by the body...not in the liver, therefore.
It is excreted whole unchanged in the urine.

Depends on what is "high".... this number has changed so many times in the
last 20 yrs...and basically changes according to DRUG companies.

You might want to read up on this:
http://www.ravnskov.nu/cholesterol.htm

Cholesterol tends to go up with age for everyone. Elderly people in general
live longer with higher cholesterol readings.
http://www.geriatrictimes.com/g040618.html

SSRI drugs can raise cholesterol, but only in certain people..it is not a common effect:
http://www.rxlist.com/cgi/generic/venlafax_wcp.htm
Quote:
Serum Cholesterol Elevation

Clinically relevant increases in serum cholesterol were recorded in 5.3% of venlafaxine-treated patients and 0.0% of placebo-treated patients treated for at least 3 months in placebo-controlled trials (see ADVERSE REACTIONS-Laboratory Changes). Measurement of serum cholesterol levels should be considered during long-term treatment.
Cymbalta which is related, has caused liver damage...
under postmarketing events for Effexor:
Quote:
Postmarketing Reports

Voluntary reports of other adverse events temporally associated with the use of venlafaxine that have been received since market introduction and that may have no causal relationship with the use of venlafaxine include the following: agranulocytosis, anaphylaxis, aplastic anemia, catatonia, congenital anomalies, CPK increased, deep vein thrombophlebitis, delirium, EKG abnormalities such as QT prolongation; cardiac arrhythmias including atrial fibrillation, supraventricular tachycardia, ventricular extrasystoles, and rare reports of ventricular fibrillation and ventricular tachycardia, including torsade de pointes; epidermal necrosis/Stevens-Johnson Syndrome, erythema multiforme, extrapyramidal symptoms (including dyskinesia and tardive dyskinesia), angle-closure glaucoma, hemorrhage (including eye and gastrointestinal bleeding), hepatic events (including GGT elevation; abnormalities of unspecified liver function tests; liver damage, necrosis, or failure; and fatty liver), interstitial lung disease, involuntary movements, LDH increased, neuroleptic malignant syndrome-like events (including a case of a 10-year-old who may have been taking methylphenidate, was treated and recovered), neutropenia, night sweats, pancreatitis, pancytopenia, panic, prolactin increased, renal failure, rhabdomyolysis, serotonin syndrome, shock-like electrical sensations or tinnitus (in some cases, subsequent to the discontinuation of venlafaxine or tapering of dose), and syndrome of inappropriate antidiuretic hormone secretion (usually in the elderly).
http://www.rxlist.com/cgi/generic/venlafax_ad.htm
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Last edited by mrsD; 05-05-2007 at 07:03 AM.
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