Quote:
Originally Posted by johnt
Banana, especially the skin, contains dopamine, see:
http://neurotalk.psychcentral.com/thread152993.html
The problem from the PD point of view is that in normal circumstances dopamine doesn't go through the BBB.
I'm surprised that more work hasn't been done to get around this problem.
John |
i stand corrected. do you eat those bananas to get dopamine?
another reason you don't want a lot of dopamine in your bloodstream is it would make you very naseaus, take too much sinemet and see how you feel. so independent of needing l-dopa to pass thru the BBB, you don't want high concentrations of dopamine stimulating your cells.
Once levodopa has entered the central nervous system (CNS), it is metabolized to dopamine by aromatic-L-amino-acid decarboxylase. However, conversion to dopamine also occurs in the peripheral tissues, causing adverse effects and decreasing the available dopamine to the CNS, so it is standard practice to co-administer a peripheral DOPA decarboxylase inhibitor.
http://perspectivesinmedicine.org/co...1/a008862.full