Ron,

As I understand it, you're telling us that you need very little levodopa, but that there's a very narrow window in which it works: too little levodopa and you're frozen, too much and you're dyskinetic.

Have you tried dispersible Madopar (levodopa, benserazide)?

Perhaps it might allow you to control your levodopa intake better.

Stocchi et al [1] report "Compared with treatment with intermittent doses of a standard oral formulation of levodopa, continuous infusion provided significant improvement in both “off periods” and dyskinesia". The bad news is that their delivery method involved "levodopa methyl ester administered via an infusion pump connected to a nasal tube placed in the duodenum". The question is: can you get some of these benefits by sipping the Madopar suspension? I don't know the answer.

I've not been prescribed this drug, so I can't report whether this works on me.

Reference

[1] "Intermittent vs Continuous Levodopa Administration in Patients With Advanced Parkinson DiseaseA Clinical and Pharmacokinetic Study"
Fabrizio Stocchi, MD, PhD; Laura Vacca, MD, PhD; Stefano Ruggieri, MD; C. Warren Olanow, MD
Arch Neurol. 2005;62(6):905-910. doi:10.1001/archneur.62.6.905.
http://archneur.jamanetwork.com/arti...ticleid=788691

John