Member
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Join Date: Sep 2011
Posts: 246
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Member
Join Date: Sep 2011
Posts: 246
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Sorry Debbie, its nothing that you won't already have heard of and I assume have already tried.
The only reference made to treatment of CRPS related movement disorders made directly in that document is in section 6.3 which only mentions treatment with baclofen and tizanidine. As I'm sure you know already, these drugs are generally not that effective for most people who have CRPS related movement disorders but they have been tried and some papers have written up their effects.
For many folk, baclofen seems to be helpful like a muscle relaxant (similar to the effect that diazepam would have but without the same dangers of rapid addiction, physical dependence and tolerance). If you have mixed tone (ie some muscles that are normal or weak and others that are tight) or muscles that constantly spasm on and off, it often just makes everything too floppy to be useful. Administration by intrathecal pump can help some people but usually those with extensive fixed dystonia where the muscles are constantly 'locked' in high tone over a large part of the body. it comes with all the dangers of invasive surgery and accidental leaking or other technical failure.
Unfortunately, these oral drugs and and the others like Dantrolene (which works at the level of the muscles rather than on the CNS) are largely the extent of the treatment options for CRPS related movement disorders. Some people with dystonia find botox injections effective but it isnt any good where it is generalised throughout your body. A very small number of people with dystonia will respond to levodopa but, like in Parkinson's disease, you have got to persevere and take it for three months minimum in order to be able to determine if it will work. People with CRPS related dystonia typically test negative for any of the known genetic defects which cause the majority of cases of dystonia.
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